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Methyl-Guard contains betaine, 5-MTHF, methyl-B12, and P5P to support healthy methylation for cardiovascular, cognitive, and bone health.* Methylation helps maintain healthy homocysteine levels.*
Serving Size: 3 Capsules
Servings Per Container: 60
Healthy Heart, Blood Vessels, Brain, and Bones
How to Use:
Take 3 capsules two times daily or as recommended by your health professional.
Betaine Anhydrous (Trimethylglycine)...........1.8g
Folate (L-5-MTHF).........................................2mg DFE
Vitamin B12 (Methylcobalamin).....................1.2mg
Vitamin B6 (Pyridoxal 5'-Phosphate).............20.4mg
Other Ingredients: Calcium (Citrate), Calcium Laurate, Hypromellose Capsule, Silicon Dioxide
The body's methylation process is key to maintaining a healthy level of homocysteine, as well as to multiple other biochemical processes involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance.* Maintaining a normal homocysteine level in the blood has joined having normal cholesterol and triglyceride levels as primary objectives for maintaining good cardiovascular health.* Because Methyl-Guard promotes healthy methylation, it helps maintain heart, blood vessel, cognitive, nerve, bone, and female reproductive health.* Methyl-Guard was the first nutritional supplement on the market to support homocysteine metabolism and healthy methylation using nutrients in their active, tissue-ready forms.*
Various conditions and stressors can have an adverse impact on the body's methylation cycle. For example, nutrient deficiencies and environmental and physical stressors can cause inefficient methylation. In addition, a common human genetic mutation that restricts the activity of a key enzyme in the body involved in methylation affects approximately 60 percent of U.S. adults. This genetic anomaly poses a significant challenge to efficient methylation - and creates an important need for nutritional support to help rectify it.
Methylation -- the addition of a methyl group (CH3 - one carbon attached to three hydrogens) to another molecule -- is an essential and vital biochemical process in the body involved in multiple biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for the process of methylation to occur effectively.*
Effective methylation must occur to maintain a normal level of homocysteine.* A deficiency in the cofactors that metabolize homocysteine is commonly seen in the elderly, thus resulting in increased homocysteine levels in the aging population. An elevated homocysteine level associated with aging, as well as less than optimal levels of folic acid and vitamins B6 and B12, often result in the inefficient methylation of numerous substances, such as DNA and proteins, which in turn decreases the integrity of vascular structures and neurons.* Providing the nutritional cofactors for the efficient metabolism of homocysteine also provides support for a healthy brain.*
A number of biochemical imbalances that raise the level of homocysteine can be addressed by supplementing with appropriate nutrient cofactors. For example, folic acid (as L-5-methyltetrahydrofolate), vitamin B12 (as methylcobalamin), and betaine (trimethylglycine) help recycle homocysteine to the amino acid methionine, while the recycling of homocysteine into the beneficial amino acids cysteine and taurine is facilitated by pyridoxal 5'-phosphate (the active form of vitamin B6).* Studies have shown these nutrients help maintain a normal level of homocysteine in the blood.*
Because homocysteine levels can be higher in individuals in which the enzymatic reaction that converts folic acid to the active methyl donor L-5-methyltetrahydrofolate (5-MTHF) does not function properly, Methyl-Guard contains 400 mcg of active 5-MTHF per capsule.*
Origin of Manufacture: USA
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*Full Refund within 30 days of purchase. *75% Refund after 30 days of purchase. *75% Credit exceeding 3 months. 10% administration fee. Shipping is paid for by the customer. Original packaging. No returns after 30 days. No Cancellations; No Returns on PPE or PPE-related products; All Sales Final. Not all products are eligible for returns. Exclusions may apply. Please refer to the "Restrictions" tab on the products listing page, i.e. where stated "Non-Returnable Item". All returns must be approved by our Returns Department. An e-mail notification will be issued regarding your return status and return instructions, should this apply. Any product returned for credit without an authorized RMA number clearly printed on the outside package or shipping label will be refused. Unauthorized returns will not be honored or accepted for credit.
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
If pregnant, consult your health professional before using this product.
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
For over 30 years, Thorne Research has been dedicated to enhancing the health and well-being of people worldwide by providing innovative, high-quality, research-based nutritional supplements, health diagnostics technology platforms, and the latest in medical education.
Through our products and services, our passionate, talented staff, collaboration with a variety of innovative and expert strategic partners, and an unwavering commitment to integrity, Thorne Research strives to become a leading health-care company serving people around the world.
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